About Sodium Valproate

This belongs to the group of medicines known as antiepileptics. Sodium Valproate controls the convulsions (fits or seizures) in some forms of epilepsy by reducing the activity in the brain. Sodium Valproate is also helpful in preventing absence seizures (where people appear to 'switch off' for short periods of time).

Sodium Valproate is also used in treatment of psychiatric disorders like Manic Episode, Bipolar Affective Disorder, Schizoaffective Disorder, Borderline Personality Disorder and Intermittent Explosive Disorder. Sodium Valproate is available in plain or enteric coated tablet and injection form.

Before Taking Sodium Valproate


➙ If you are pregnant, trying for a baby, or breast-feeding,

➙ If you or anyone in your family has ever suffered from liver problems,

➙ If you suffer from kidney problems, Systemic Lupus Erythematosus (SLE) or Diabetes,

➙ If you suffer from Porphyria (a blood disorder),

➙ If you have ever had an allergic reaction to this or any other medicine,

➙ If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to Take Sodium Valproate

➙ Take Sodium Valproate exactly as directed by your doctor.

➙ Always read the manufacturer's information leaflet, if possible, before beginning treatment.

➙ Do not stop taking Sodium Valproate without speaking to your doctor first. Your doctor will need to reduce the dose you are taking gradually.

➙ Do not take indigestion remedies at the same time of day as the enteric coated tablets. Take them at least one hour before or one hour after a dose of Sodium Valproate.

➙ Sodium Valproate enteric coated and modified release tablets must be swallowed whole with a glass of water.

➙ Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of Sodium Valproate contact your doctor or go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.

➙ Sodium Valproate is for you. Never give it to others, even if their condition appears to be the same as yours.

Advice for women

➙ Women who can become pregnant should not start treatment with Sodium Valproate without specialist advice.

➙ Women who are already taking Sodium Valproate and are planning a family or have an unplanned pregnancy should get specialist advice concerning the risk of harm to the unborn child.

➙ If the decision is made to use Sodium Valproate treatment during pregnancy it is best used on its own and not in combination with other antiepileptics. The specialist will review your treatment and dosage requirements and monitor your progress.

➙ Women who are planning a family should seek advice about folic acid supplements before stopping contraception.

Getting the most from your treatment

➙ If you have Diabetes: Sodium Valproate can affect the results of your urine tests and you may need to carry out blood tests instead.

➙ Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside Sodium Valproate

Can Sodium Valproate cause problems ?

Along with their useful effects all medicines can cause unwanted symptoms. These usually improve as your body adjusts to the new medicine. Speak to your doctor or pharmacist if any of the following symptoms continue or become troublesome.

Tummy upset, feeling sick, unsteadiness, shakiness, confusion, increased appetite and weight gain, water retention (e.g. swollen ankles), thinning of the hair, skin rashes, irregular periods or none at all.

Important: If you experience jaundice (yellowing of the skin and whites of the eyes), severe vomiting (being sick), stomach pain, loss of appetite, drowsiness and seizures (fits) or if you experience fever (high temperature), a sore throat, mouth ulcers or unusual bruising or bleeding contact your doctor or go to the accident and emergency department of your local hospital immediately.

The strict definition of PTSD is that the trauma you had or witnessed must be severe. For example: a severe accident, rape, a life-threatening assault, torture, seeing someone killed, etc. However, symptoms similar to PTSD develop in some people after less severe traumatic events.

It is estimated that up to 1 in 10 people may develop PTSD at some stage in life. It is much more common in certain groups of people.

If you experience any other worrying symptoms, which you think may be due to this medicine, discuss them with your doctor or pharmacist.

How to store Sodium Valproate :-

➙ Keep out of reach of children.

➙ Store in a cool, dry place, away from direct light and heat.

➙ Never keep out of date or unwanted medicines. Discard them safely out of the reach of children or take them to your local pharmacist who will dispose of unwanted medicines for you.


Clinic Address (Shalimar Bagh)

Monday to Saturday
Timing : 10.30 AM to 01.15 PM
Address : Sri Ganesh Psychiatry and Physiotherapy Clinic AB-206, Shalimar Bagh, New Delhi - 88
For Appointment : +91-93132 06395
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Clinic Address (Rohini)

Monday to Saturday
Timing : 06.30 PM to 08.30 PM
Address : CSC -7, Shop No - 40, DDA Market, First Floor, Near F3 Block, Sector - 16, New Delhi - 85
For Appointment : +91-95607 66242
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Frequently Asked Questions

Q. What are the common types of headache?

Headache is a very common disease. Common headache are due to migraine, tension headache, chronic daily headache, cluster headache. This is also due to increased blood pressure. Other causes of continuous headache are depression and persistent stress.

Q. What is the treatment of headache?

Treatment of headache depends on diagnosis. To diagnose it proper history taking and enquiry about work and associated stress is very important. Before starting treatment we must rule out medical cause of headache by investigations. For example dull, severe and continuous headache must be ruled out by brain radio investigation.

Q. What are the common types of headache?

Headache is usually of two types primary and secondary. Primary headache is independent in nature and it could be episodic and continuous. Most common cause of episodic headache is migraine, cluster headache and tension headache. Continuous headache could be due to chronic daily headache and depression and stress.

Q. What is secondary headache?

Secondary headache is due to blood pressure, Tumour, post head injury and subarachnoid haemorrhage etc.

Q. What is depression?

Depression is a state of mind in which person biological function like sleep, appetite and bowel habit are disturbed along with low energy lack of interest in work, surrounding and socialisation. It also leads to helplessness, hopelessness and worthlessness. In severe case person start thinking about suicide. Long standing depression may lead to social cut-off and loss of jobs as well.

Q. What are symptoms in lay term when one can understand he is going through depression?

In less educated people multiple somatic symptoms such as headache, body ache , gas formation , unexplained other symptoms , sleep disturbance , heaviness or lightheadedness are common symptoms . Educated or intelligent people will complain of lack energy, lack of charm or meaning in life, fatigued feeling, hopelessness and worthless feeling along with sleep disturbance and lack or increased appetite are usual symptoms.

Q. What are the common symptoms of depression?

 Symptoms of depression can be classified into following groups.

(A) DEPRESSED MOOD- this is hallmark of all depression regardless of other associated symptoms. It is sustained emotional state that is characterised by sadness, low morale, misery, discouragement, hopelessness, emptiness, distress, pessimism etc. it is different in quantitative term as it is more intense than normal emotional response in bad situation.

(B) ANHEDONIA- is loss of interest. Patient is unable to draw pleasure from previously enjoyable activities. In severe cases they abandon   most of the things they valued in life.

(c)COGNITIVE SYMPTOMS- difficulty in concentrating, negative thoughts, low self-esteem and self-confidence, suicidal idea are some most common cognitive symptoms. In severe case delusions of nihilism are also present.

(D) PSYCHOMOTOR DISTURBANCE - It can be aggression, agitation or retardation. Aggression is usually associated with irritability and restlessness. Retardation is associated with lack of initiative, mask like facial expression, emotional sluggishness and increased time to answer in response to question.

(E)VEGETATIVE SYMPTOMS - this is characterised by increased sleep or decreased sleep, increased appetite or decreased appetite, decreased libido and motivation.

(F) ANXIETY SYMPTOMS- are usually part of depression.

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